𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Immunogenetic study on the polymorphism of serum α2-lipoproteins in mink. I. Identification and genetic control of five Lpm allotypes

✍ Scribed by O. K. Baranov; M. A. Savina; D. K. Belyaev

Publisher
Springer
Year
1976
Tongue
English
Weight
990 KB
Volume
14
Category
Article
ISSN
0006-2928

No coin nor oath required. For personal study only.

✦ Synopsis

Five allotypes, Lpm 1, Lpm 2, Lpm 3, Lpm 4, and Lpm 5, were detected by isoimmunization in mink sera. Immunoelectrophoresis, preparative ultracentrifugation, and histochemical tests for lipids and esterase permitted reference of these alloantigenic markers to a very high density alpha2-lipoprotein. Based on population analysis and breeding tests, five genetic units are postulated: Lpm1, Lpm4, Lpm3,4, Lpm1,2, and Lpm2,4,5. These units determine the polymorphism of the Lpm system and behave as Mendelian alleles.

📜 SIMILAR VOLUMES

Immunogenetic study on the polymorphism
Immunogenetic study on the polymorphism of serum α2-lipoprotein in mink. III. Ld1 allotype of low-density lipoprotein
✍ O. K. Baranov; M. A. Savina 📂 Article 📅 1979 🏛 Springer 🌐 English ⚖ 405 KB

Mink Ldl antigen of serum low-density lipoprotein was demonstrated by alloantibodies. No genetic relation was found between Ldl and the Lpm system of very-high-density lipoprotein. The existence of an autosomal dominant gene, coding for the new alloantigenic marker, is postulated on the basis of min

Immunogenetic study on the polymorphism
Immunogenetic study on the polymorphism of serum α2-lipoproteins in mink. II. Identification of allotypesLpm-7andLpm-8and genetic control of seven markers of theLpmsystem
✍ O. K. Baranov; V. I. Yermolaev; D. K. Belyaev 📂 Article 📅 1978 🏛 Springer 🌐 English ⚖ 746 KB

By means of alloimmunization of mink, two new antigens, Lpm-7 and Lpm-8, were detected in their sera. Lpm-7 and Lpm-8 allospecificities were referred to a very high density alpha2-lipoprotein (Lpm) by the following criteria: histochemical tests, immunoelectrophoresis, preparative ultracentrifugation

Immunogenetic study on the polymorphism
Immunogenetic study on the polymorphism of serum α2-lipoproteins in mink. IV. Diallelism at theLdlocus of low-density lipoprotein
✍ O. K. Baranov; M. A. Savina 📂 Article 📅 1981 🏛 Springer 🌐 English ⚖ 994 KB

Antibodies against a new allotype, Ld2, of mink low-density lipoprotein (LDL) were obtained by alloimmunization with a preparation of this lipoprotein. The two known allotypes of LDL, designated Ld1 and Ld2, are coded for by codominant alleles of the autosomal Ld locus. This locus is probably involv