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Immunogenetic study on the polymorphism of serum α2-lipoprotein in mink. III. Ld1 allotype of low-density lipoprotein

✍ Scribed by O. K. Baranov; M. A. Savina

Publisher
Springer
Year
1979
Tongue
English
Weight
405 KB
Volume
17
Category
Article
ISSN
0006-2928

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✦ Synopsis

Mink Ldl antigen of serum low-density lipoprotein was demonstrated by alloantibodies. No genetic relation was found between Ldl and the Lpm system of very-high-density lipoprotein. The existence of an autosomal dominant gene, coding for the new alloantigenic marker, is postulated on the basis of mink breeding data.

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Immunogenetic study on the polymorphism
Immunogenetic study on the polymorphism of serum α2-lipoproteins in mink. IV. Diallelism at theLdlocus of low-density lipoprotein
✍ O. K. Baranov; M. A. Savina 📂 Article 📅 1981 🏛 Springer 🌐 English ⚖ 994 KB

Antibodies against a new allotype, Ld2, of mink low-density lipoprotein (LDL) were obtained by alloimmunization with a preparation of this lipoprotein. The two known allotypes of LDL, designated Ld1 and Ld2, are coded for by codominant alleles of the autosomal Ld locus. This locus is probably involv

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✍ O. K. Baranov; M. A. Savina; D. K. Belyaev 📂 Article 📅 1976 🏛 Springer 🌐 English ⚖ 990 KB

Five allotypes, Lpm 1, Lpm 2, Lpm 3, Lpm 4, and Lpm 5, were detected by isoimmunization in mink sera. Immunoelectrophoresis, preparative ultracentrifugation, and histochemical tests for lipids and esterase permitted reference of these alloantigenic markers to a very high density alpha2-lipoprotein.

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✍ O. K. Baranov; V. I. Yermolaev; D. K. Belyaev 📂 Article 📅 1978 🏛 Springer 🌐 English ⚖ 746 KB

By means of alloimmunization of mink, two new antigens, Lpm-7 and Lpm-8, were detected in their sera. Lpm-7 and Lpm-8 allospecificities were referred to a very high density alpha2-lipoprotein (Lpm) by the following criteria: histochemical tests, immunoelectrophoresis, preparative ultracentrifugation