Immunoelectronmicroscopical localization of a lysosomal and a brush-border enzyme in Caco-2 cells
โ Scribed by J. Klumperman; J.A.M. Fransen; J.C. Dorsman; H.P. Hauri; R.P.J. Oude Elferink; J.M. Tager; L.A. Ginsel
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 201 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0304-3991
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The effect of a single oral dose of pp'DDT (100 mg/kg body wt.) has been studied on the intestinal uptake of certain nutrients and on brush border enzymes in rats. Intestinal uptake of leucine, and phenylalanine was considerably increased but there was no change in the absorption of glucose and alan
Caco-2 cells, which are known to spontaneously differentiate in cell culture, adopt typical epithelial characteristics and are widely used as a model to study cellular uptake, transport and metabolism processes. However, groups of flat and undifferentiated cells have been observed amid differentiati