Minor Histocompatibility (mH) antigens are polymorphic endogenously synthesized products that can be recognized by alloreactive T cells in the context of major histocompatibility complex molecules. In transplant situations where tissue donor and recipient are matched for HLA, mH antigens may trigger
Immunodominant minor histocompatibility antigens: the major ones
β Scribed by Claude Perreault; Denis C Roy; Claudette Fortin
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 165 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0167-5699
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Cytotoxic effector T cells putatively specific for multiple non-H-2 histocompatibility (H) antigens were generated by immunizing and boosting C57BL/6 and B6.C-H-2 d mice with BALB.B and BALB/c stimulator cells, respectively. The generated effectors were tested for cell-mediated lympholysis on a pane
## Abstract The present experiments analyze the functional properties of helper T cells specific for βminorβ histocompatibility antigens. T cells from C3H/HeJ mice, primed __in vivo__ and highly enriched __in vitro__ for reactivity to membrane antigens of C3 H/Tif B cells, specifically proliferate,