✦ LIBER ✦

Immunocytochemistry of serotonin-containing nerves in the human gut

✍ Scribed by S. S. Kurian; G. -L. Ferri; J. Mey; J. M. Polak

Publisher: Springer
Year: 1983
Tongue: English
Weight: 807 KB
Volume: 78
Category: Article
ISSN: 1432-119X
DOI: 10.1007/bf00496204

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✦ Synopsis

An immunocytochemical technique, using L-tryptophan enhancement and paraformaldehyde fixation, has been successfully applied for the demonstration of serotonin-containing neurons in the human enteric nervous system. Throughout the intestine, serotonin-immunoreactive nerves were mainly detected in the myenteric plexus and, to a smaller extent, in the submucous plexus, while hardly any nerve fibres were seen in the mucosa. This approach provides a useful tool for the investigation of neuropathological conditions of the gut.

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