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Immunochemical studies of organ and tumor lipids. I. The production of antibodies against a lipid hapten by injection of the mitochondrial fraction of rat lymphosarcoma

✍ Scribed by Maurice M. Rapport; Liselotte Graf

Publisher: John Wiley and Sons
Year: 1955
Tongue: English
Weight: 761 KB
Volume: 8
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(1955)8:3<538::aid-cncr2820080313>3.0.co;2-g

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## WITH THE TECHNICAL ASSISTANCE OF N THE preceding paper6 it was shown that I injection of the mitochondria1 fraction of rat lymphosarcoma into rabbits produces relatively high titered antisera reacting with a lipid fraction extractable from the whole tissue with chloroform-methanol. There were t

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T IS A WELL established phenomenon that I the antibodies produced in rabbits by the injection of certain mammalian tissue fractions may react with alcoholic extracts of the tissue. The nature of the reactive substances in the alcoholic extracts is not known, but by virtue of their similarity in extr