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Immunochemical Properties of Ubiquitin Conjugates in the Paired Helical Filaments of Alzheimer Disease

โœ Scribed by George Perry; Paul Mulvihill; Victor A. Fried; Harry T. Smith; Inge Grundke-Iqbal; Khalid Iqbal

Book ID
111175331
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
730 KB
Volume
52
Category
Article
ISSN
0022-3042

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High resolution analysis of paired helic
High resolution analysis of paired helical filaments in Alzheimer's disease
โœ Wen, G. Y. ;Wisniewski, H. M. ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 932 KB

Results of this comparative study indicated that electron microscopy of supra-ultrathin sectipns provided the best resolution; revealing the subunit structures, globules (32 A +4), and longitudinal bars (47 A f6) of paired helical filaments (PHF). A three-dimensional model of PHF substructure is the