Immunochemical analysis of Lewis rat antisera to the synthetic encephalitogenic peptide S49
โ Scribed by Eugene D. Day; George A. Hashim; Nicholas T. Potter; Kenneth J. Lazarus
- Book ID
- 105027345
- Publisher
- Springer
- Year
- 1985
- Tongue
- English
- Weight
- 869 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0364-3190
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The rationale for designing and synthesizing 24 different peptide analogs and subpeptides of residues 69-84 of guinea pig myelin basic protein is presented. The encephalitogenic potential of 19 of these peptides in Lewis rats is also given.
Immunochemical analysis of polyclonal antisera from Lewis rats immunized with peptide analogs and subpeptides of residues 72-84 of guinea pig myelin basic protein (MBP) indicated that there were four main epitopic specificities involved: one represented by residues 76-80, one by residues 72-74, one