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Immunization to a syngeneic sarcoma by a monoclonal auto-anti-idiotypic antibody

✍ Scribed by Forstrom, J. W.; Nelson, K. A.; Nepom, G. T.; Hellström, I.; Hellström, K. E.

Book ID
109731176
Publisher
Nature Publishing Group
Year
1983
Tongue
English
Weight
392 KB
Volume
303
Category
Article
ISSN
0028-0836

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A syngeneic anti-idiotype monoclonal antibody (MAb) (CM-I I) directed against an anti-carcinoembryonic antigen (CEA) murine MAb (NP-4) was evaluated as a second antibody (SA) to promote the rapid clearance of radiolabeled NP-4 from the blood. Initial studies confirmed that CM-I I IgG removed l3Il-NP