Immunization and the decline of viral hepatitis as a cause of acute liver failure
β Scribed by Maria Sjogren
- Book ID
- 111722377
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 72 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
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A 46-year-old patient diagnosed with chronic myeloid leukemia in whom cytogenetic and molecular remission had never been achieved was commenced on Imatinib Mesylate (GleevecΓ’, Novartis Pharmaceuticals Corp., East Hanover, NJ). After 18 months of treatment, she developed abnormal liver function tests
Despite extensive investigations, the cause of liver injury in 14% of patients with acute liver failure remains unknown (indeterminate). In a pilot study using a novel assay, highly specific acetaminophen-cysteine adducts were detected in 7 of 36 indeterminate patients (19%). To extend these observa