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Immune system expression of SLURP-1 and SLURP-2, two endogenous nicotinic acetylcholine receptor ligands

โœ Scribed by Yasuhiro Moriwaki; Ken Yoshikawa; Hiromi Fukuda; Yoshihito X. Fujii; Hidemi Misawa; Koichiro Kawashima


Book ID
116718971
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
495 KB
Volume
80
Category
Article
ISSN
0024-3205

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## Abstract Mammalian secreted lymphocyte antigenโ€6/urokinaseโ€type plasminogen activator receptorโ€related peptideโ€1 (SLURPโ€1) is a positive allosteric ligand for ฮฑ7 nicotinic acetylcholine (ACh) receptors (ฮฑ7 nAChRs) that potentiates responses to ACh and elicits proapoptotic activity in human kerat