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Expression of the endogenous, nicotinic acetylcholine receptor ligand, SLURP-1, in human colon cancer

✍ Scribed by A. Pettersson; S. Nordlander; G. Nylund; A. Khorram-Manesh; S. Nordgren; D. S. Delbro


Book ID
111197722
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
473 KB
Volume
28
Category
Article
ISSN
1474-8665

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## Abstract Mammalian secreted lymphocyte antigen‐6/urokinase‐type plasminogen activator receptor‐related peptide‐1 (SLURP‐1) is a positive allosteric ligand for Ξ±7 nicotinic acetylcholine (ACh) receptors (Ξ±7 nAChRs) that potentiates responses to ACh and elicits proapoptotic activity in human kerat