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Immune selection of tumor cells in TCR β-chain transgenic mice

✍ Scribed by Silaeva, Yulia Yu.; Grinenko, Tatyana S.; Vagida, Murad S.; Kalinina, Anastasia A.; Khromykh, Ludmila M.; Kazansky, Dmitry B.

Book ID
121760880
Publisher
Informa plc
Year
2013
Tongue
English
Weight
524 KB
Volume
11
Category
Article
ISSN
1547-691X

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✍ Hanspeter Pircher; Pamela Ohashi; Guido Miescher; Rosemarie Lang; Athanasios Zik 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 988 KB

## Abstract To study allelic exclusion of TcR genes we analyzed two types (I and II) of TcR β transgenic mice. T cells derived from both types of mice contained similar amounts of transgenic RNA transcripts; however, surface expression of the transgenic β chain was drastically reduced in type II co