Immune Response to a Synegeneic Rat Tumour: Evolution of Serum Cytotoxicity and Blockade
โ Scribed by Flannery, G R; Chalmers, P J; Rolland, J M; Nairn, R C
- Book ID
- 109833212
- Publisher
- Nature Publishing Group
- Year
- 1973
- Tongue
- English
- Weight
- 790 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0007-0920
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## Abstract Sera from rats bearing transplanted aminoazoโdyeโinduced hepatomas inhibited the cytotoxicity of lymphโnode cells from tumourโimmune rats for plated hepatoma cells, when the sera were incubated with the effector cells, rather than target cells. In contrast, sera from hepatomaโimmune rat
## Abstract Serum from hepatomaโbearing rats has been shown to abrogate the cytotoxicity of immune lymphโnode cells when added to the target cells (blocking) or the effector cells (inhibition). Neutralization of these in vitro blocking and inhibitory reactions by sera containing antibody to tumour