𝔖 Bobbio Scriptorium
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Immune regulation and control of regulatory T cells by OX40 and 4-1BB

✍ Scribed by Takanori So; Seung-Woo Lee; Michael Croft


Book ID
116401101
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
502 KB
Volume
19
Category
Article
ISSN
1359-6101

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## Abstract TNF is a pleiotropic cytokine with intriguing biphasic pro‐inflammatory and anti‐inflammatory effects. Our previous studies demonstrated that TNF up‐regulated FoxP3 expression and activated and expanded CD4^+^FoxP3^+^ regulatory T cells (Tregs) via TNFR2. Furthermore, TNFR2‐expressing T