Costimulation of human CD28β T cells by
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Jacob Bukczynski; Tao Wen; TaniaβH. Watts
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Article
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2003
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John Wiley and Sons
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English
β 305 KB
## Abstract The T cell surface protein CD28 provides a critical costimulatory signal for T cell activation. With age, humans accumulate increasing numbers of CD28^β^ T cells, and this loss of CD28 expression is exacerbated certain disease states, such as HIV infection, autoimmune conditions or canc