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Immune function in prolidase deficiency

โœ Scribed by M. A. Cleary; M. Heaney; J. M. Couriel; J. H. Walter


Publisher
Springer
Year
1994
Tongue
English
Weight
188 KB
Volume
17
Category
Article
ISSN
0141-8955

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Inactivation of recombination activating gene (RAG)-1 or RAG-2 in mice results in the inability of developing lymphocytes to initiate V(D)J recombination, leading to the arrest of lymphocyte differentiation at a very early stage. Introduction of functionally assembled antigen-receptor genes or other