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Immortalized cells from the rat suprachiasmatic nucleus express functional melatonin receptors

✍ Scribed by Moisés A. Rivera-Bermúdez; Monica I. Masana; Gregory M. Brown; David J. Earnest; Margarita L. Dubocovich


Book ID
113499411
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
366 KB
Volume
1002
Category
Article
ISSN
0006-8993

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Primary cultured cells from the presumptive anlage of the rat suprachiasmatic nucleus (SCN) were immortalized by infection with a retroviral vector encoding the adenovirus 12S E1A gene. After drug selection, the resulting neural cell lines (SCN1.4 and SCN2.2) displayed (a) extended growth potential