A combination of Monod kinetics and diffusion equation was used for evaluating the effectiveness factor for immobilized cells on solid supports. This has revealed that there is an optimal value of biofilm thickness which results in a maximum for the effectiveness factor. The optimal value of biofi
Immobilization of growth factors on solid supports for the modulation of stem cell fate
β Scribed by Pompe, Tilo; Salchert, Katrin; Alberti, Kristin; Zandstra, Peter; Werner, Carsten
- Book ID
- 109946875
- Publisher
- Nature Publishing Group
- Year
- 2010
- Tongue
- English
- Weight
- 799 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1750-2799
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## Abstract We have studied the effect of recombinant human Stem Cell Factor (SCF) on the growth of human peripheral blood, bone marrow, and cord blood progenitor cells in semisolid medium. While SCF alone had little colonyβstimulating activity under fetal bovine serum (FBS)βdeprived culture condit