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Imidazoline I1 receptor-mediated reduction of muscle rigidity in the reserpine-treated murine model of Parkinson's disease

โœ Scribed by Mitsuo Tanabe; Masako Hashimoto; Hideki Ono


Book ID
113587693
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
602 KB
Volume
589
Category
Article
ISSN
0014-2999

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## Abstract The present study was designed to determine the potential of CB1 cannabinoid receptor modulating compounds in the treatment of Lโ€3,4โ€dihydroxyphenylalanine (Lโ€dopa)โ€“induced dyskinesia in Parkinson's disease. In the reserpineโ€treated rat model of parkinsonism, administration of a high do