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Striatal Cannabinoid CB1 Receptor mRNA Expression Is Decreased in the Reserpine-Treated Rat Model of Parkinson's Disease

✍ Scribed by M.A. Silverdale; S. McGuire; A. McInnes; A.R. Crossman; J.M. Brotchie


Book ID
115607499
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
145 KB
Volume
169
Category
Article
ISSN
0014-4886

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## Abstract The present study was designed to determine the potential of CB1 cannabinoid receptor modulating compounds in the treatment of L‐3,4‐dihydroxyphenylalanine (L‐dopa)–induced dyskinesia in Parkinson's disease. In the reserpine‐treated rat model of parkinsonism, administration of a high do