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Imidazole Derivatives. XXVIII. Synthesis and Antitumor Activity of 4(5)-[4-(3,3-Dimethyl-1-triazeno)-3-nitrophenyl]imidazole and Related Compounds

โœ Scribed by M. A. Iradyan; N. S. Iradyan; G. M. Stepanyan; F. G. Arsenyan; B. T. Garibdzhanyan


Book ID
110291670
Publisher
Springer
Year
2001
Tongue
English
Weight
68 KB
Volume
35
Category
Article
ISSN
0091-150X

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An efficient and convenient synthesis of
โœ D. Farquhar; J. A. Benvenuto; Ti Li Loo ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 279 KB ๐Ÿ‘ 1 views

Reaction of dimethylamine 14C with a four-fold molar excess of 5-diazoimidazole-4-carboxamide in methanol followed by column chromatography of the product on basic a1 umina afforded 5-3,3-dimethyl-4C-l-triazeno)imi datole-4-carboxamide in 70-75% yield and greater than 99.9% radiochemical purity. The