Imidazenil, a new drug for the management of convulsions in organophosphate intoxication in rodents

✍ Scribed by Rump, Slawomir; Gidynska, Teresa; Galecka, Elzbieta; Antkowiak, Oktawiusz; Kowalczyk, Marek

• Book ID: 101215733
• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 82 KB
• Volume: 55
• Category: Article
• ISSN: 1526-498X
• DOI: 10.1002/(sici)1096-9063(199910)55:10<1033::aid-ps43>3.0.co;2-h

✦ Synopsis

coupling of agonist binding to gating of the ion channel, indicating that agonist binding and subsequent ion channel opening are separate, but related processes. Phy differentially displaces [ 125 I]a-BGT from the chimeric nAChR, suggesting that the b subunit is not involved in Phy binding, and that Phy targets the insect agonist binding loop C.