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Development of a New Quantitative Approach for the Isobolographic Assessment of the Convulsant Interaction Between Pefloxacin and Theophylline in Rats

✍ Scribed by Laurence M. Levasseur; Annie Delon; William R. Greco; Pascal Faury; Serge Bouquet; William Couet

Book ID
110307587
Publisher
Springer US
Year
1998
Tongue
English
Weight
743 KB
Volume
15
Category
Article
ISSN
0724-8741

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This work proposes a model to characterize the additivity or the nonadditivity of combinations of more than two agents. Using a Bayesian framework, we modeled the variability between experimental subjects, the errors that occurred during data collection, and the relationship between effects and conc