Imatinib dose escalation to achieve molecular responses in patients with chronic myeloid leukemia in late chronic phase
β Scribed by F. Stagno; P. Vigneri; V. Del Fabro; S. Stella; M. Massimino; S. Berretta; A. Messina; F. Di Raimondo
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 82 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0145-2126
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π SIMILAR VOLUMES
Chronic myeloid leukaemia (CML) patients in chronic phase (CP) are currently treated with a standard dose of imatinib of 400mg/daily. However, once in complete cytogenetic remission (CCR) it is possible that some patients maintain this status with reduced dose of the drug. Here, we describe five cas
## Abstract Imatinib mesylate is the gold standard treatment of chronic myeloid leukaemia (CML) and 400βmg/day is considered the standard dose. Although it is generally well tolerated, some patients require temporary drug discontinuation and permanent dose reduction because of haematological or non