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Imaging of human SCLC with radiolabelled monoclonal antibodies against EMBP in a nude mouse model

Book ID: 122789826
Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 36 KB
Volume: 7
Category: Article
ISSN: 0169-5002
DOI: 10.1016/0169-5002(91)91601-7

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## Abstract Monoclonal antibody UJ13A radiolabelled with isotopes of iodine has been shown to selectively localize to human neuroblastoma xenografts. When ^131^I‐UJ13A conjugates were given to nude mice at high doses (100–150 μCi), tumours temporarily disappeared, only to regrow. No selection for n