Marrow cells may enter megakaryocytes by a phenomenon that is referred to as emperipolesis. While the morphological appearance of this process is quite striking, its etiology and pathophysiological significance is uncertain. Emperipolesis is most often described in association with neoplastic disor
Images in hematology: Psychogenic purpura
โ Scribed by Moll, Stephan
- Book ID
- 101214396
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 173 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0361-8609
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โฆ Synopsis
A 48-year-old woman with no previous bleeding problems presented with a 1-year history of spontaneous skin bruising. Her bruises always developed in a typical pattern: Without antecedent event, she would experience a sudden localized ''stinging, popping, and pulsating'' sensation in her skin over the extremities or trunk. The surrounding skin would feel very warm, turn diffusely red, and itch intensely. Within minutes, a bruise would appear and enlarge over 20-30 mins. The associated symptoms would subside after approximately 2 hr, after which the patient would feel extremely exhausted. The bruises would disappear after several weeks.
The patient had multiple emotional stresses, including localized breast cancer diagnosed 2 years before onset of the bruising (free of disease after treatment), a pending medical law suit, loss of a job held for more than 20 years, and significant marital problems with a pending law suit for divorce. She saw a psychiatrist and was treated for depression. There was no evidence of domestic physical violence. Physical examination was unremarkable, except for the illustrated skin findings. Image A shows a ''bruise''
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Parkinson's syndrome (PS) is frequently encountered in disorders associated with prominent degeneration of the nigrostriatal pathway as in Parkinson's disease, multisystem atrophy, and progressive supranuclear palsy (presynaptic PS). Drug-induced parkinsonism, a common, underdiagnosed health problem