## Abstract We assessed the status of dopamine nerve terminals in patients treated with dopamine receptor blocking agents (DRBAs) who had developed drugβinduced parkinsonism (DIP). We performed [^123^I]FPβCIT SPET in 32 consecutive patients who were on DRBAs for at least 6 months and developed extr
DAT imaging in drug-induced and psychogenic parkinsonism
β Scribed by Eduardo Tolosa; Miguel Coelho; Marisol Gallardo
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 68 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0885-3185
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β¦ Synopsis
Parkinson's syndrome (PS) is frequently encountered in disorders associated with prominent degeneration of the nigrostriatal pathway as in Parkinson's disease, multisystem atrophy, and progressive supranuclear palsy (presynaptic PS). Drug-induced parkinsonism, a common, underdiagnosed health problem and psychogenic parkinsonism are causes of Parkinson's syndrome which, evidence suggests, occurs without degeneration of nigrostriatal structures. We review clinical features and results of DAT imaging in drug-induced parkin-sonism and psychogenic parkinsonism. These two conditions normally give normal striatal DAT imaging results; an abnormal result in either case could exclude both conditions, corroborating a diagnosis of organic parkinsonism in uncertain cases.
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The results of two epidemiological studies suggest a hereditary predisposition to develop drug-induced parkinsonism. We investigated human leukocyte antigen (HLA) antigen prevalence rates in patients with neurolepticinduced parkinsonism. Fifty-two male, white, neuroleptic-treated, chronic inpatients
## Abstract We describe three patients who presented with 4 to 5 Hz tremors of the suprahyoid region of the neck. Two developed their tremors in association with levosulpiride treatment. When they opened their mouths, the neck tremors disappeared; no tongue tremors were observed. However, a videofl
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