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Image quality and focal lesion detection on T2-weighted MR imaging of the liver: Comparison of two high-resolution free-breathing imaging techniques with two breath-hold imaging techniques

✍ Scribed by Seung Soo Lee; Jae Ho Byun; Hye-Suk Hong; Seong Ho Park; Hyung Jin Won; Yong Moon Shin; Moon-Gyu Lee


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
359 KB
Volume
26
Category
Article
ISSN
1053-1807

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✦ Synopsis


Abstract

Purpose

To evaluate image quality and accuracy for the detection of focal hepatic lesions depicted on T2‐weighted images obtained with two high‐resolution free‐breathing techniques (navigator‐triggered turbo spin‐echo [TSE] and respiratory‐triggered TSE) and two standard‐resolution breath‐hold techniques (breath‐hold TSE with restore pulse and half‐Fourier acquisition single‐shot TSE [HASTE]).

Materials and Methods

Our institutional review board approved this study, and written informed consent was obtained from all patients. Two readers independently reviewed 200 T2‐weighted imaging sets obtained with four sequences in 50 patients. Both readers identified all focal lesions in session 1 and only solid lesions in session 2. The readers' confidence was graded using a scale of 1–4 (1 ≤ 50%; 4 ≥ 95%). The diagnostic accuracies of the four MR sequences were evaluated using the free‐response receiver operating characteristic (ROC) method. Region‐of‐interest (ROI) measurements were performed for the mean signal intensity (SI) in the liver, spleen, hepatic lesions, and background noise.

Results

The accuracy of navigator‐triggered TSE and respiratory‐triggered TSE was superior to that of breath‐hold TSE with restore pulse and HASTE for the detection of all focal or solid hepatic lesions. The mean lesion‐to‐liver contrast‐to‐noise ratio (CNR) of solid lesions in navigator‐triggered (P < 0.001) and respiratory‐triggered TSE (P < 0.005) was significantly higher than that in HASTE.

Conclusion

High‐resolution, free‐breathing, T2‐weighted MRI techniques can significantly improve the detectability of focal hepatic lesions and provide higher lesion‐to‐liver contrast of solid lesions compared to breath‐hold techniques. J. Magn. Reson. Imaging 2007. © 2007 Wiley‐Liss, Inc.


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