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IL-7 improves reconstitution of CD4 T cells, including cytomegalovirus-specific CD4 T cells, in lymphopenic monkeys*1

✍ Scribed by STOREK, J

Book ID: 119273405
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 24 KB
Volume: 113
Category: Article
ISSN: 1097-6825
DOI: 10.1016/j.jaci.2003.12.143

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## Abstract The initial requirement for the emergence of CMV‐specific CD8^+^ T cells is poorly understood. Mice deficient in the cosignaling TNF superfamily member, 4‐1BB, surprisingly developed exaggerated early CD8^+^ T‐cell responses to mouse CMV (MCMV). CD8^+^ T cells directed against acute MCM