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IL-6-transfected tumor cells modulate the status of CD8+ and CD4+ T cells to control tumor growth

โœ Scribed by Chia-Ling Hsieh; Shih-Jen Liu; Chia-Rui Shen; Mei-Yu Chen; Shu-Ching Hsu; Jy-Ping Tsai; Yi-Shiuan Li; Ching-Jen Yang; Pele Chong; Hsin-Wei Chen


Book ID
116569452
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
323 KB
Volume
215
Category
Article
ISSN
0171-2985

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## Abstract Spontaneous tumors frequently express antigens that can be recognized by the immune system but nevertheless manage to evade immune surveillance. To better understand the mechanism of evasion, we followed CD8 and CD4 T cells reacting against a subcutaneously growing tumor, modified to ex