IL-33 and ST2 in pregnancy failure: the new kids on the block
β Scribed by I.L. Sargent; G. Granne; T. Child; C.W.G. Redman; J. Southcombe
- Book ID
- 113753311
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 64 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0165-0378
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## Background: St2 has been proposed to be a regulator of inflammation and th1/th2 balance. st2l is the il-33 membrane receptor and belongs to the il-1r family. the soluble variant, st2s, is identical to the extracellular region of st2l and competes for il-33 binding, inhibiting receptor signaling.