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IL-23 up-regulates IL-10 and induces IL-17 synthesis by polyclonally activated naive T cells in human

✍ Scribed by Serge Vanden Eijnden; Stanislas Goriely; Dominique De Wit; Fabienne Willems; Michel Goldman


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
195 KB
Volume
35
Category
Article
ISSN
0014-2980

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IL-10 produced by activated human B cell
✍ Jean-David Bouaziz; Sebastien Calbo; Maud Maho-Vaillant; Anne Saussine; Martine πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 328 KB

## Abstract IL‐10‐producing regulatory B cells have been identified in mice and shown to downregulate inflammation, making them potentially important for maintenance of tolerance. In this study, we isolated B cells from human blood and spleen, and showed that after a short period of __ex vivo__ sti