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IL-20 Gene Expression Is Induced by IL-1β through Mitogen-Activated Protein Kinase and NF-κB-Dependent Mechanisms

✍ Scribed by Otkjaer, Kristian; Kragballe, Knud; Johansen, Claus; Funding, Anne T; Just, Helle; Jensen, Uffe B; Sørensen, Lotte G; Nørby, Peder L; Clausen, Jes T; Iversen, Lars


Book ID
110049788
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
254 KB
Volume
127
Category
Article
ISSN
0022-202X

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## Abstract Breakdown of the extracellular matrix (ECM) is accomplished by the concerted action of several proteases, including the urokinase plasminogen‐activator (uPA) system and matrix metalloproteinases (MMPs), which is crucial for cancer invasion and metastasis. Several reports have shown that