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IL-1β signalling in glial cells in wildtype and IL-1RI deficient mice

✍ Scribed by Lisa C Parker; Giamal N Luheshi; Nancy J Rothwell; Emmanuel Pinteaux


Book ID
110007298
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
286 KB
Volume
136
Category
Article
ISSN
0007-1188

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## Abstract ## BACKGROUND The principal components of the interleukin‐1 (IL‐1) family are two secreted factors (IL‐1α and IL‐1β), two transmembrane receptors (IL‐1RI [biologically active] and IL‐1RII [inert receptor]), and a natural antagonist receptor of IL‐1 function (IL‐1Ra). Changes in the exp