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Differential susceptibility to lethal endotoxaemia in mice deficient in IL-1α, IL-1β or IL-1 receptor type I

✍ Scribed by LEO A.B. JOOSTEN; FRANK L. VAN DE VEERDONK; ALIEKE G. VONK; OTTO C. BOERMAN; MONIQUE KEUTER; GIAMILLA FANTUZZI; INEKE VERSCHUEREN; TOM VAN DER POLL; CHARLES A. DINARELLO; BART JAN KULLBERG; JOS W.M. VAN DER MEER; MIHAI G. NETEA

Book ID: 109344118
Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 301 KB
Volume: 118
Category: Article
ISSN: 0365-5555
DOI: 10.1111/j.1600-0463.2010.02684.x

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## Abstract Inflammation and genetics may play a role in the pathogenesis of febrile seizures (FSs). We aimed to test whether interleukin‐1β (IL‐1β), IL‐1 receptor antagonist (IL‐1 Ra), IL‐6 promoter, IL‐8, IL‐10, or tumor necrosis factor (TNF) gene polymorphisms could be used as markers of suscept