HMGB-1 induces IL-6 production in human
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Chun-Han Hou; Yi-Chin Fong; Chih-Hsin Tang
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Article
📅
2011
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John Wiley and Sons
🌐
English
⚖ 589 KB
## Abstract High mobility group box chromosomal protein 1 (HMGB‐1) is a widely studied, ubiquitous nuclear protein that is present in eukaryotic cells, and plays a crucial role in inflammatory response. However, the effects of HMGB‐1 on human synovial fibroblasts are largely unknown. In this study,