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IL-12/23p40-dependent clearance of Anaplasma phagocytophilum in the murine model of human anaplasmosis

โœ Scribed by Joao H.F. Pedra; Jian Tao; Fayyaz S. Sutterwala; Bindu Sukumaran; Nancy Berliner; Linda K. Bockenstedt; Richard A. Flavell; Zhinan Yin; Erol Fikrig


Book ID
109308267
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
215 KB
Volume
50
Category
Article
ISSN
0928-8244

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## Abstract **BACKGROUND:** Ustekinumab is a human monoclonal antibody that binds to the p40 subunit of interleukin (IL) 12 and ILโ€23 and inhibits their pharmacological activity. To evaluate potential effects of ustekinumab treatment during pregnancy, developmental studies were conducted in cynomol