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IL-10 induces suppressor of cytokine secretion-3 (SOCS-3) and ILT-3 in human endothelial cells and inhibits T cell costimulation

✍ Scribed by C Gleissner; A Zastrow; R Klingenberg; N Xia; T.J Dengler


Book ID
117710164
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
49 KB
Volume
22
Category
Article
ISSN
1557-3117

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## Abstract Effects of IL‐10 on endothelium‐dependent T cell activation have not been investigated in detail. We confirm expression of the IL‐10 receptor and effective signaling __via__ STAT‐3 in human umbilical vein endothelial cells (HUVEC). In CD4 T cell cocultures with HUVEC, pretreatment of en