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Human endothelial T cell costimulation is inhibited by interleukin 10 (IL-10) through induction of suppressor of cytokine secretion-3 (SOCS-3) and ILT-3

โœ Scribed by C.A Gleissner; A Zatrow; R Klingenberg; N Xia; T.J Dengler


Book ID
116517657
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
96 KB
Volume
23
Category
Article
ISSN
1557-3117

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IL-10 inhibits endothelium-dependent T c
โœ Christianโ€„A. Gleissner; Arne Zastrow; Roland Klingenberg; Martinโ€„S. Kluger; Math ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 628 KB

## Abstract Effects of ILโ€10 on endotheliumโ€dependent T cell activation have not been investigated in detail. We confirm expression of the ILโ€10 receptor and effective signaling __via__ STATโ€3 in human umbilical vein endothelial cells (HUVEC). In CD4 T cell cocultures with HUVEC, pretreatment of en