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IL-1 receptor antagonist (IL-1Ra) KO mice show anxiety-like behavior

โœ Scribed by Chisato Wakabayashi; Yoichiro Iwakura

Book ID
116775757
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
95 KB
Volume
58
Category
Article
ISSN
0168-0102

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Three molecular forms of the IL-1 receptor antagonist (IL-1ra) have been identified and cloned. Secreted IL-1ra (sIL-1ra or IL-1ra1) contains a classical leader peptide giving a released mature protein. Two intracellular isoforms, icIL-1ra type I (IL-1ra2) and icIL-1ra type II (IL-1ra3), have no lea