Characterization of type II intracellula
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Marta Muzio; Nadia Polentarutti; Fabio Facchetti; Giuseppe Peri; Andrea Doni; Ma
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Article
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1999
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John Wiley and Sons
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English
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Three molecular forms of the IL-1 receptor antagonist (IL-1ra) have been identified and cloned. Secreted IL-1ra (sIL-1ra or IL-1ra1) contains a classical leader peptide giving a released mature protein. Two intracellular isoforms, icIL-1ra type I (IL-1ra2) and icIL-1ra type II (IL-1ra3), have no lea