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IL-1 and IL-1 receptor gene expression in the mouse CNS

✍ Scribed by László Takács; Bálint Kacsóh; Lynn A. Bristol

Book ID
119108533
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
100 KB
Volume
43
Category
Article
ISSN
0165-5728

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## Abstract Interleukin‐1 (IL‐1) is a key pro‐inflammatory cytokine that has diverse actions in the brain as a regulator of host defense responses and a mediator of inflammation. Two major agonists, IL‐1α and IL‐1β, bind to a single known functional type‐1 IL‐1 receptor (IL‐1RI) that associates wit