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Ii-Key/HPV16 E7 hybrid peptide immunotherapy for HPV16+ cancers

✍ Scribed by Minzhen Xu; Xueqing Lu; Margaret Sposato; John W. Zinckgraf; Shuzhen Wu; Eric von Hofe

Book ID
116961663
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
522 KB
Volume
27
Category
Article
ISSN
0264-410X

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## Abstract The cellular tumor suppressor p16 is strongly overexpressed in cervical cancers and precancers. We have previously demonstrated that infiltrating T lymphocytes reactive against p16 can be found in cervical cancer patients. Here, we analyzed whether p16 induces humoral immune responses.