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Disappearance of antibodies to HPV 16 E7 after treatment for cervical cancer

✍ Scribed by Joakim Dillner


Book ID
119065715
Publisher
The Lancet
Year
1993
Tongue
English
Weight
167 KB
Volume
341
Category
Article
ISSN
0140-6736

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Antibody response to HPV16 E7 oncoprotein may represent a marker of cervical cancer. A HPV16 GST-E7 fusion protein was used in a Western Blot assay to analyse the HPV16 E7 antibody response in 30 patients before and after treatment for cervical carcinoma (stage IIB or IIIB). Patients were treated wi

Serological responses to HPV 16 in cervi
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Sera from patients with cervical cancer, cervical intraepithelial neoplasia (CIN) and non-genital cancers, and from healthy individuals, were investigated for antibodies to human papilloma virus (HPV) early proteins E4, E6 and E7 and the major capsid protein LI by Western blot analysis of recombinan