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Ihproved information about the composition of the active site of heart sarcolemmal (Na++K+)-ATPase

✍ Scribed by A. Ziegelhöffer; A. Breier; R. Monošíková

Book ID
119442507
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
87 KB
Volume
19
Category
Article
ISSN
0022-2828

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It is demonstrated a fast and significant depression in the sarcolemmal (Na,K)-ATPase activity that occurs as early as 25 sec after the onset of Ca2+ depletion, and participates in the development of Ca(2+)-paradox in the rat heart. Pretreatment of the animals with 7-oxo-prostacyclin (PGI2) 24-48 h