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IGF-I and TGF-1 application by a poly-(D,L-lactide)–coated cage promotes fusion in the sheep cervical spine


Book ID
119615893
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
39 KB
Volume
2
Category
Article
ISSN
1529-9430

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✍ G. Schmidmaier; B. Wildemann; M. Lübberstedt; N.P. Haas; M. Raschke 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 229 KB 👁 1 views

## Abstract Previous __in vivo__ studies revealed a stimulating effect of locally applied IGF‐I and TGF‐β1 released from poly(D,L‐lactide)‐coated titanium implants on rat and porcine fracture healing. The purpose of the present study was to evaluate the effect of IGF‐I (5% w/w) and TGF‐β1 (1% w/w)