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IGF-I and FGF-2 coordinately enhance cyclin D1 and cyclin E–cdk2 association and activity to promote G1 progression in oligodendrocyte progenitor cells

✍ Scribed by Terra J Frederick; Teresa L Wood


Book ID
116735154
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
904 KB
Volume
25
Category
Article
ISSN
1044-7431

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Synergistic induction of cyclin D1 in ol
✍ Terra J. Frederick; Jungsoo Min; Stefanie C. Altieri; Nina E. Mitchell; Teresa L 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 742 KB

## Abstract D‐type cyclins are direct targets of extracellular signals and critical regulators of G~1~ progression. Our previous data demonstrated that IGF‐I and FGF‐2 synergize to enhance cyclin D1 expression, cyclin E/cdk2 complex activation, and S‐phase entry in OP cells. Here, we provide a mech