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IGF-1, IGFBP-3, and cancer risk

✍ Scribed by Andrew G Renehan; Marcel Zwahlen; Sarah T O'Dwyer; Stephen M Shalet; Matthias Egger

Book ID
117286687
Publisher
The Lancet
Year
2004
Tongue
English
Weight
41 KB
Volume
364
Category
Article
ISSN
0140-6736

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## Abstract Conditions related to chronic hyperinsulinemia, such as obesity, noninsulin dependent diabetes mellitus and polycystic ovary syndrome, are associated with an increased risk of endometrial cancer. Elevated plasma IGF‐I and decreased levels of IGF‐binding proteins have been shown to be as