Idiotypic properties of the murine anti-arsonate antibody response: B- and T-cell influences
β Scribed by John D. Conger; George K. Lewis; Joel W. Goodman
- Book ID
- 113133365
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 568 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0008-8749
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## Abstract A small dose of the IgG~1~ fraction of antiβidiotypic antibody (ΔId 1) raised in guinea pigs against a strain A/J antibody specific for streptococcal Group A carbohydrate sensitizes A/J mice against Group A streptococci. This is opposed to the previously established suppressive function
Antibodies directed against idiotypic determinants of the cell-surface IgM of a 6 lymphoma, 38c. were effective in delaying development of the tumor and in some instances in preventing its growth. The efficacity of the anti-idiotype antibodies was markedly increased when they were injected in combin